锌和汞同属ⅡB族无素  ，二者之间化学物质质地还有一个定同质性性  ，能其他人市场竞争缓和而相互之间换置 。目前BB贝博艾弗森官方网站汞污染日益严重  ，孕妇和胎儿是最容易受危害的群体 。有研究发现孕期汞暴露与新生儿体质量呈负相关  ，高汞暴露孕妇不良妊娠结局(早产、胎膜早破、小于胎龄儿)的发生率更高 。因此  ，如何防治汞的胚胎毒性  ，对优生优育具有重要指导意义 。研究表明  ，甲基汞可以通过激活ASK1/NK信号通路引起细胞凋亡 。同时治疗组胎盘组织的细胞凋亡率、促凋亡蛋白Bax的表达均较病例组下降   ，而凋亡抑制蛋白Bc-2 的表达则较病例组升高  ，表明锌（乳酸锌Zinc Lactate、氨基酸螯合锌Zinc Amino Acid Chelate、精氨酸锌Zinc Arginate）可能通过调控凋广相关蛋白Bcl-2/Bax的表达而抑制细胞凋亡  ，从而拮抗汞对孕妇及胎儿的毒性作用 。

孕早期补锌（乳酸锌Zinc Lactate、氨基酸螯合锌Zinc Amino Acid Chelate、精氨酸锌Zinc Arginate）对汞致毒的拮抗反应

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Antagonistic effect of zinc supplementation during pregnancy (zinc lactate, zinc amino acid chelate, zinc arginine) on mercury toxicity

Zinc and mercury belong to the same group of ⅡB elements. They have certain similarities in chemical properties and can compete and inhibit each other and replace each other. At present, environmental mercury pollution is becoming increasingly serious, and pregnant women and fetuses are the most vulnerable groups. Studies have found that mercury exposure during pregnancy is negatively correlated with the weight of newborns, and the incidence of adverse pregnancy outcomes (premature birth, premature rupture of membranes, and small for gestational age) is higher in pregnant women with high mercury exposure. Therefore, how to prevent and control the embryotoxicity of mercury is of great guiding significance for eugenics. Studies have shown that methylmercury can cause cell apoptosis by activating the ASK1/NK signaling pathway. At the same time, the apoptosis rate and expression of the pro-apoptotic protein Bax in the placenta tissue of the treatment group were lower than those in the case group, while the expression of the apoptosis inhibitor protein Bc-2 was higher than that in the case group, indicating that zinc (zinc lactate, zinc amino acid chelate, zinc arginine) may inhibit apoptosis by regulating the expression of apoptosis-related protein Bcl-2/Bax, thereby antagonizing the toxic effects of mercury on pregnant women and fetuses.

Antagonistic effect of zinc supplementation during pregnancy (zinc lactate, zinc amino acid chelate, zinc arginine) on mercury toxicity

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